Wednesday, November 11, 2009

BYBS: PodCastle


PodCastle: Fantasy short stories in podcast form

I had decided up front that I was not going to like the latest story from PodCastle, "The Small Door," but I ended up changing my mind.

The story is about "...weirdos, children (the two are not mutually exclusive), and a very small door."  In particular it is about the investigations of two young girls into what a rather strange neighbor is doing with a bunch of small animals.  It was written by Holly Phillips and performed (read) by Tina Connolly.

At first brush I was thinking "I hate self-conscious young girl crap which is obviously what this story is about."  The story sucked me in though and I found myself feeling a mixture of dread and curiosity as to the outcome.

One thing that I found very interesting were the emotions it inspired.  I normally expect a story to make me envision the scene and the characters, but this one reminded me that they can make you feel as well.  The suspense comes from not being sure what the characters were going to find.  The complications because one of the characters is prevented from doing something fun because of her sister.  The different way that I "looked" at things after the outcome.

This is all stuff that I knew a story could do, but it has been a while since one made me feel that way.

I can't go into more details without giving away the story (or at least that's my story), but PodCastle is wonderful site with lots of very good stories.  What's more they have some very good performers reading them.  Tina Connolly reads this one and does an excellent job*.

PodCastle's definition of a "fantasy story" is pretty broad so if you find that one story is not to your liking, listen to a couple of others before writing them off.

Till next time, avoid gnomes...and small doors.

* = for those of you that think the reader makes any difference, think of how many times you've been happy with your first try at a greeting for your answering machine or voicemail.


Monday, October 12, 2009

BYBS: Viral Gene Therapy

Now that we are heading into the flu season I thought it was appropriate to talk about how wonderful viruses are.

Maybe they're not, but I thought it would be nice to talk about how wonderful some viruses are.  Specifically, using the power of the little buggers to help monkeys and, one hopes, people with various problems. 

One area I find particularly fascinating is the area of viral gene therapy.  The idea is to use a virus as way of sending genes to cells of an animal after they are mature.  While some genes are only important for the structure and growth of an organisms, other genes affect the way that an organism functions after it is grown.  In the case described in the Science News article, the genes enable the eyes of a grown monkey to detect frequencies of light that they could not previously see. 

This particular study has all kinds of implications. The article is mostly about how neurologists were surprised that a full grown monkey's visual system could accommodate the new colors. The thing I find really cool is the almost offhand way that using a virus is being used in this experiment.

During my lifetime, I have seen the concept of using viruses for this sort of thing go from the realm of theory to the point where it barely raises an eyebrow. 

Then there is the whole meddling with the human genome business, but I think I can stretch that out into a whole other posting.

At any rate, I like this sort of news.  I find the ability of humanity to turn something that is often times an agent of destruction (think disease causing viruses) into an agent of help.

Tuesday, October 06, 2009

BYBS: Coloring Books for the Soul

While talking to a friend (a man can hope can't he?) about stories I mentioned how I would make up alternate endings or fill in character motivations. He asked if that was a big part of the story and I remarked in a rare moment of clarity that, for me, that sort of thing is the story.

If a song is sad I tell myself why. If I find a character in a movie interesting, I might envision a few extra scenes for them. And, of course, we've all had that moment where we come up with some fiction for why people behave in real life.

Another aspect of art is that the importance or motivation that we place on some things are completely out of proportion to what the artist may have intended. There's the interview with the singer who, it turns out, does not actually write their own songs. The star who does not behave at all the way that we think they should based on their performance in a movie.

Like a Rorschach test, the meaning we place on art is more indicative of the reader/viewer/listener than it may be of the art itself.

Monday, September 28, 2009

BYBS: Brain Science Podcast

So I was, as usual, trying to find a topic to blog about. It being Monday morning at 6am, and therefore just a wee bit past Sunday (though the whole BYBS thing is as much of an excuse to get me to do something as anything else, but that's another story) and I was debating whether to blog about a kick-butt Podcastle episode or a kick-butt episode of Brain Science Podcast.

I finally settled on Brain Science Podcast, specifically episode number 59: Interview with Guy Caldwell. This is mostly because Dr. Caldwell brings a certain enthusiasm to what others might consider to be a boring topic: worms.

In particular, he talks about a worm called caenorhabditis elegans, or C. elegans as this critter goes by at cocktail parties. C. elegans has a number of distinctions which make it useful to scientists like the fact that the complete cell lineage for the critter has been determined.

Can you imagine the people who had to do that job?!

Cell number 2,643...check...2644...check...2645...check.

I would gasp with disbelief at the mind-numbing nature of that job if it were not for a) the unbelievably boring nature of many jobs that people do and b) I'm not sure that this critter actually has that many cells.

Anyhow, one of the cool things this guy managed to do with C. elegans is to paste some jellyfish genes that give off light into the neurons of the worm so that one could, for example, see if some combination of conditions was causing said neurons to die off. That, in turn, came in handy for helping to tease out some aspects of Parkinson's disease.

Put another way, you could take a look at a worm and ask a simple question like: "Hey is the thing glowing? No? Then all the dopamine producing neurons are dead." This is much simpler than getting a worm analyst to talk to the thing.

It's stuff like this that wins the "aint it cool?" category for extreme cleverness, but then there's the whole issue of Dr. Caldwell's enthusiasm for the subject. I mean it sounds like he actually enjoys this work.

As someone who at times feels like a burn-out, chewed up, dehydrated husk of a human being, listening to someone with that sort of vigor brings back fond memories. He speaks with admiration for the guys who sat there and catalog cell lineages. He talks about how his research could be used to create therapies for Parkinson's disease.

That's the kind of energy and optimism, the looking forward to tomorrow that I find inspiring.

Monday, September 21, 2009

BYBS: Oatmeal, Raisins and Black Tea

Over here at the office for extreme cleverness and ideas for when you have nothing else to blog about, I've been researching a new substance that has the potential to bring about world peace and freedom in our time. Many people have asked me how this works.

The answer is simple: it doesn't.

So much for the bad news. The good news is that the byproduct, oatmeal with raisins using black tea instead of hot water, is surprisingly tasty. What's more, it gets both carbohydrates and caffeine into one compact meal.

While this may seem like a trivial posting, you have to remember the source. Furthermore, when facing yet another day in which my full potential will be utilized in a manner which makes me realize that I don't have that much potential, and that will simultaneously bring home the notion that we all have something to contribute except for those like myself who can best help out by not contributing, the concept of a caffeine loaded breakfast is just the thing to get the wheels turning.

Wednesday, September 09, 2009

BYBS: Microbe World

Last week (OK, it was actually the week before that, but still), I listened to a fascinating podcast called "Tiny Conspiracies" by Dr. Bonnie Bassler about how some microbes can talk to each other. I found this very cool because a) the little buggers aren't supposed to be able to do that and b) I could understand anything she said at all.

As a veteran of listening to people who are not coherent, it is always a pleasure to experience a presentation given by someone who does a good job. Many people have complained to me about my postings, saying that they go off on tangents and have no point. To these people I say: "I'm supposed to have a point?"

But back to small critters talking to each other. It was previously thought that microbes led sad, lonely lives concerned with things like growing, dividing, and causing plague. During the past 20 years or thereabouts, it has been discovered that bacteria and their ilk also do things like engage in vibrant conversations, write books and attend poetry readings...and then cause plague.

So perhaps I embellished that a bit. Perhaps a lot. But it appears that microbes do not live the isolated lives that we once imagined. In "Tiny Conspiracies" Dr. Bassler talks about how some microbes can do things like gauge the size of their population and then change their behavior accordingly.

For example, once a population has reached a critical limit, the colony can form a membrane around themselves for added protection. Another, rather more sinister example is that a colony of bacteria might wait to release a toxin until their population is large enough that it will have a better chance of overcoming their host.

This sort of info gets the "ain't it cool!" award from me partially because of the clever way Dr. Bassler describes some of their tests --- she used bits of DNA that would cause the microbes to light up when they were "talking" --- but also for the potential applications. If one were to interfere with this signaling mechanism, for example, it may be possible to cause some nasty pathogen to skip the whole "cause plague" bit.

So waltz on over to Microbe World and give Tiny Conspiracies a listen.

Thursday, September 03, 2009

BYBS: Escape Artists

Escape Pod and its siblings, Podcastle and Pseudopod are podcast sites that deal in various fiction short stories.

A podcast is like a radio show or a book on tape in a form that you can download and play on your computer, an MP3 player or an iPod (hence the name). Much to my surprise, I've never blogged about podcasts before, but that just means that I now have all my BYBS entries written for the next 6 weeks.

Escape Pod deals in podcasts about science fiction, while Pseudopod deals in horror stories and Podcastle has essentially everything else. I've tried listening to fiction podcasts before and, though there have been exceptions, I've come to believe very strongly in what Theodore Sturgeon meant when he said "90% of everything is crap."

I was therefore more than a little surprised when I stumbled onto these guys. The stories are very interesting and original, and most are read by good performers. Incidentally, if you don't think that voice talent should make a difference, go over to librivox.org to hear some person suck the soul out of Charles Dickens.

I don't want to babble on about all the good stories I've heard there (read: topic for weeks of BYBS entries), but here are a few:

  • Episode 212: Skinhorse Goes to Mars by Mike Boris - a Mars overrun by zombies holds the key to a terraforming experiment gone horribly wrong.
  • Episode 210: The Hastillan Weed by Ian Creasey - you know about all the nasty plants that have been imported to other climates and wrought havoc? Ever wonder what a plant from another planet might do?
  • Episode 209: On the Eyeball Floor by Norm Sherman - a story about love and jealousy in a not quite human way

And that's just from the science fiction podcast! Get yourself an iPod and check em out.